Nutramigen vs Puramino

Nutramigen vs Puramino: Which is the best?

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Parents turn to formulas for various reasons. Our business is to help you arrive at the choice of a formula that does you and your baby a whole world of good. If you have Nutramigen vs Puramino baby formulas in mind, it might interest you to find out what differentiates one from the other.  Thankfully, this is what you get from reading this article; a comprehensive analysis of both products, and how each meets your baby’s specific needs.

Nutramigen Vs Puramino


Nutramigen is a hypoallergenic formula designed for babies between the ages of 0-12 months who suffer from fussiness due to cow’s milk protein sensitivity. It addresses the issue of colic, milk intolerance, and food allergies. Nutramigen contains hydrolyzed milk protein and iron, which supply your baby with the nutrient she needs for growth.


  • Nutramigen is a #1 Pediatrician recommended formula
  • It is dairy-free but contains hydrolyzed milk protein. This makes it proper for babies who are lactose intolerant.
  • Nutramigen is richly fortified with iron.
  • It comes with DHA and ARA, which are essential fatty acids and the same nutrients found in breast milk to support your baby’s mental and sight development.
  • Nutramigen is not as expensive as its ready-to-feed counterpart.
  • There is corn maltodextrin (33%) to provide maximum nutrition for your baby


  • Nutramigen has an unpleasant flavor, and this could make feeding it to your baby difficult.
  • It makes your baby gassy and irritable.
  • Nutramigen is a no-go area for babies who are allergic to corn.
  • It may produce runny and greenish feces in some babies.
  • Nutramigen has soy oils and may provoke an allergic response in babies.


Puramino, an infant formula designed by Enfamil, is hypoallergenic in function. Like Nutramigen, it is designed specially for babies who are either allergic or intolerant to cow’s milk protein allergy. It provides 3.6 grams of fat and is made of tapioca starch. Puramino offers a rich proportion of protein and a little more sugar than Nutramigen.


  • A hypoallergenic amino acid-based formula for infants suffering from severe cow’s milk protein and multiple food allergies.
  • It is rich in protein and fat and works for babies with elemental diet needs.
  • While the infant range offers no flavor, Puramino junior range comes with an option of vanilla flavor.
  • It tastes a lot better than Nutramigen, and will easily appeal to your little one.
  • Puramino is lactose-free and free of ingredients with the potential to trigger gluten allergies or celiac disease.
  • Highly fortified with iron
  • Can serve as the main source of nutrition for your baby until she turns 6 months of age.
  • Puramino comes with DHA and ARA, which occur in breast milk and promote mental and eye development.


  • Like Nutramigen, it is quite pricey.
  • It contains soy which may trigger allergies in sensitive babies.


Nutramigen and Puramino are both efficient products from Enfamil. They are both more specific in action in that while the former works for babies with food protein allergies, the latter serves babies who cannot put up with an extensively hydrolyzed formula like Nutramigen. Your pediatrician’s recommendation, and definitely your baby’s needs, will be the verdict.

Switching From Nutramigen To Puramino; What You Need To Know

Before switching to Puramino, it is important to know that it is not a regular but an amino acid-based formula designed for babies with multiple food allergies. However, do well to consult your pediatrician before making the switch. It is safer to let an expert ascertain the situation in question, so you don’t have to beat around the bush.

Although Puramino is quite expensive, it is one formula that will give your baby an enviable body and mind growth and can last her well until her second year birthday.

Puramino Equivalents

Puramino is an amino acid-based product formulated for babies who are allergic to food substances such as soy, gluten, milk, and others. If you are looking for its equivalents in other brands or products, here they are;

  • Similac Elecare
  • Nestle Alfamino
  • Nutricia Neocate
  • EquaCare Jr.
  • Essential Care Jr

All formulas mentioned above are ideal equivalents to Puramino, and you can opt for any of them if there is a shortage of Puramino. However, make sure to hear your pediatrician’s thoughts before setting out for an equivalent.

Puramino Formula Side Effects

Of course, to every positive, there is a negative, and Puranimo is no exclusion. The bright sides are not without side effects. And these include inconsistency in;

  • Poop color; you may find it change to yellow, green, or khaki.
  • Poop consistency.
  • Bowel movement frequency.
  • Digestion, feeding.
  • Gas, discomfort, and fussiness.
  • Reflux, Constipation, or Spit-up.

The aforementioned side effects are mostly temporary issues that naturally accompany the transition to an amino acid-based formula. Ordinarily, the side effects should subside once your baby finally gets used to the formula. Importantly, do not sleep on your Pediatrician’s advice.

Nutramigen Formula Side Effects

In the first few days or weeks of starting your baby on Nutramigen, some side effects may surface in;

  • Slight changes in stool patterns.
  • Diaper rash
  • Weight loss
  • Sleeplessness
  • Gas and or spitting up.
  • Frequency of loose stools especially in the early starting days.
  • Greenish stools, which is quite normal if your baby is on iron-fortified formula.

These are mostly temporary side effects, and your baby should get better with time. Again, be sure to seek your pediatrician’s opinion before making a formula move.

Bottom Line

Nutramigen vs Puramino is an interesting competition, mainly because they are from the same maker. They are even both hypoallergenic and formulated for babies with special needs. Here is where the line is drawn; while Nutramigen is for babies with cow’s milk allergy, Puramino takes it up a notch by working for babies with multiple food allergies. This article provides everything you need to know about both products.

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